The omnadren 250 resultsl in the formulation – nasal spray metered, very rarely has side effects.
According to the World Health Organization adverse reactions are classified according to their rate of development as follows: very common and very rare; the frequency is unknown – according to available data to set the frequency of occurrence was not possible. The respiratory system: very common: irritation of the mucous membrane of the nasal cavity. At the beginning of therapy in the following phenomena can be observed within a short period of time: rhinorrhea, and the formation of crusts on the mucous membrane, nose bleeding; often: . sneezing after the first use of the drug, dyspnea, hoarseness, wheezing, pain in nose, bleeding from the nose, the part of the immune system is very rare:anaphylactic reactions.
On the part of the gastrointestinal tract : common: dry mucous throat membranes. On the part of the system of the skin and subcutaneous tissue: rare: hypersensitivity reactions of immediate and delayed type (including urticaria, rash, dermatitis, pruritus, angioedema). General disorders and changes in the injection site: uncommon: candidiasis of the nasal cavity and upper respiratory tract, with prolonged use – atrophy of the nasal mucosa, especially during prolonged therapy; very rare: ulcerations of nasal mucosa, perforation of nasal septum. Some omnadren 250 results symptoms may be masked due to the use of corticosteroids. when long-term administration of high doses of budesonide can not eliminate the risk of manifestation of systemic effects, including Cushing’s syndrome, symptoms kushingoida, adrenal suppression, growth retardation in children and adolescents, decrease in bone mineral density, the symptoms of hypothyroidism or Cushing, cataract and glaucoma. It is also possible: nausea, change in taste, difficulty swallowing, anosmia, palpitations, nasal congestion, dizziness, headache, sore throat, conjunctival hyperemia, myalgia, drowsiness, cough. More rarely there may be deviation of psychological and behavioral issues, including psychomotor hyperactivity, sleep disorders, anxiety , depression or aggression (particularly in children).
Accidental overdose in the dosage form of a nasal spray metered, does not cause any obvious symptoms.
Acute overdose is unlikely.
With prolonged use of high doses, as well as the simultaneous reception of other glucocorticosteroids may appear in Cushing’s symptoms. In this case, the drug should be discontinued gradually reducing the dose.
Interaction with other drugs
The simultaneous use of the drug omnadren 250 results with inducers of microsomal oxidation (phenobarbital, phenytoin, rifampin) may decrease the effectiveness of the first.
Dianabol, estrogens, ketoconazole increase the effect of budesonide. Itraconazole can cause increased plasma concentrations of budesonide.